The Hormonal Symphony

The numerous different hormones produced in the body are each very potent individually, but it is also vital that they work together to maintaining one’s health and stamina.

Take estrogen and testosterone, for example. Estrogen alone helps protect against heart disease, osteoporosis, Alzheimer’s and incontinence, as well as enhancing libido, skin tone, emotional well-being, cognitive acuity, sensory function and digestion. Testosterone improves libido and energy levels, enhances a sense of well-being, strengthens bones, builds muscle, and promotes muscle tone, brain function, and heart health.

Or consider DHEA and Cortisol. DHEA works closely with Cortisol to protect against stress, cardiovascular disease, osteoporosis, and Alzheimer’s; as well as preventing wrinkles and dry eyes, increasing libido, raising energy levels, and boosting memory and immunity. Cortisol helps regulate blood pressure, increases energy and influences metabolism, as well as helps your body cope with stress and infection.

Having diminished hormone levels contributes to a litany of symptoms and a slow, steady deterioration in one’s health. As years pass, these symptoms become even more noticeable: diminished libido, waning energy, decreased lean muscle and increased body fat, weakened bones and osteoporosis, reduction in skin tone and elasticity, memory lapses, cardiovascular concerns, sleeplessness, irritability and mood swings, among several others. The relationship between hormone levels and these symptoms becomes undeniable.

Hormones perceptibly alter physical, sexual and cognitive functions, often with psychological complications. Until recently, these changes were accepted as “growing old,” forcing individuals into the background. Outwardly, a middle-aged man may have increased abdominal fat and reduced lean muscle mass—hallmarks of hormone imbalance. He no longer looks or feels virile, as his sexual functions fade. As a result, self-esteem begins to suffer. The story isn’t that different for women. In fact, both genders suffer when hormone imbalances develop, which results in physical and emotional stress.

In addition to impacting personal life, hormone imbalances and their effects encroach on job performance and business success. That’s best seen in the corporate world, where poor lifestyle choices, a diminished endocrine system and 21st century stress collide. On the way to fiscal nirvana, high performers notoriously “spend their health to gain wealth.” They labor over business strategies to ensure corporate success, leaving their health behind. The most costly event in their lives—loss of productivity— goes unnoticed. Eventually, poor nutrition, reduced exercise and overly prescribed antidepressants (coupled with plummeting hormone levels) take their toll in both the personal and corporate setting.

The fact is, losing critical personnel proves incredibly costly. It’s estimated that 70% of all deaths in the U.S. each year are due to chronic diseases, which account for more than 83% of the $2 trillion spent on health care annually. The effect on any company’s bottom line can be significant. That’s why savvy corporations are championing a corporate culture that fosters better health and subsequently improves productivity.

We now realize delaying premature disabilities is viable, since the body’s hormone receptors don’t lose their ability to respond to hormone messages. These receptors are waiting to be filled. Restoring hormonal balance with hormone optimization and healthier lifestyle choices really can turn the tide.

For example, both genders experience menopause. Male menopause (called andropause) is subtler than its female counterpart. Sparked by a decline in androgens (male sex hormones), male menopause typically begins in the 40s. Female menopause (marked by a dynamic drop in estrogen and testosterone levels) occurs at a definitive point in time, while male menopause moves stealthily over a period of 20 years. Nonetheless, both genders battle the same symptoms mentioned earlier. However, in the male aging process, there are compound challenges. Testosterone output decreases approximately l%-3% per year, starting at age 30. Men also begin to form more estrogen, which stores in fat. A typical 50-year-old male at normal weight has more estrogen than his female, postmenopausal counterpart. These higher estrogen levels ultimately compete with testosterone for the same receptors. In addition, an increase in sex hormone-binding globulins (SHBG) takes up even more of the free testosterone. This loss of testosterone contributes to a middle-aged man’s “pot belly” and reduced muscle tone. The differences between the sexes are quantitative, not qualitative. Both genders may need additional hormones to get their bodies back in balance, if testing reveals diminished levels.

Hormonal health plays an intricate part in determining overall well-being. The endocrine system—made up of hormone-secreting glands— often is overlooked in conventional healthcare. Since it regulates our internal environment and maintains system integration, the endocrine system demands attention. Eight major endocrine glands comprise this system, communicating from various points throughout the body. Although all glands have secondary and tertiary functions, the following list focuses on their primary ones.

  • pituitary gland — regulating other endocrine glands
  • pineal glands — regulating biological rhythms, moods and stimulating puberty
  • thyroid gland –regulating metabolic rate
  • parathyroid glands — regulating blood calcium
  • adrenal glands — regulating fluid and sodium balance, as well as warning of stress
  • pancreas — producing hormones, such as insulin
  • gonads — testes or ovaries involved in sex organ functions and secondary sex characteristic development

There are many other components of the system where hormones are being created and secreted into parts of the body—such as the stomach, small intestine and heart. These also provide hormonal activity to help regulate physiological function. The relationships among endocrine glands causes them to work together with a unified purpose and function, releasing chemical messengers that impart cellular instructions.

Think of it as a symphony orchestra, playing Beethoven’s Ninth Symphony. Producing this beautiful work takes 100 instruments and a large choir. All must perform in perfect balance-without one instrument, section or singer eclipsing the others.

That is how Cenegenics® approaches endocrine therapy, believing all the “instruments” should play together harmoniously: the hormonal symphony. Hormones produced in the endocrine glands and other places in the body circulate through the bloodstream. Hormones interact with receptor proteins of specific enzymes, igniting biological responses in target tissues. Cellular activity changes and is dispatched across the plasma membrane. Every hormone has specificity, housing an individual chemical form corresponding to a particular receptor protein. When the two meet, they interlock like puzzle pieces. This receptor protein can exist in different organ cells, so the body can use the same hormone for various effects.

A complex negative-feedback pathway regulates fluctuating hormone levels. As hormone levels rise, the pathway is inhibited to maintain homeostasis. Regulation depends both on production levels plus the excretion and metabolism of hormones. A number of other factors stimulate or inhibit hormonal secretions:

  • environmental changes
  • plasma concentrations of nutrients/ions
  • neuron/mental activity

The entire endocrine system can significantly impact your ability to enjoy youthful aging and vigorous health. At Cenegenics®, we concentrate on reducing levels of two major age-promoting and degenerative disease-promoting hormones: insulin and Cortisol. We also work, in concert with nature. stimulating the body to make its own needed hormones. We are vehemently against the use of foreign substances, frequently used to mimic our hormone activity—as used traditionally in conventional practices. To the largest extent possible, we supplement with hormones that function as closely as humanly possible to hormones produced by the body.

Hormonal evaluation and relevant therapy, with a conscientious program of lifestyle management, can set a course to vitality, better sleep, an enhanced libido and sexual performance, improved cognitive function, an enhanced immune system, improved skin tone and facial appearance.


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