Estrogen in Men

Men need a certain amount of estrogen. But if a male body converts more testosterone to estrogen than required, the levels become too high. This occurs through a process called aromatization. Aromatase (found in skin, brain, fat, and bone) transforms the hormone into estrogen (estradiol). Consequently, the estrogen interferes with whatever free testosterone exists and both hormones compete for receptor sites As years pass, increasingly more testosterone converts to estradiol, leading to prostate cancer, heart disease and stroke.

There are three naturally occurring estrogens: estradiol, estrone and estriol. For men, estradiol begins in the testes as well as through extra-glandular conversion of androgens. Estrogen levels increase with age, so men never need estrogen therapy. On the contrary, aging men often suffer dual effects of too little testosterone and estrogen dominance. The resulting imbalance directly causes many debilitating health and performance problems associated with normal aging. As men age, testosterone increasingly converts to estrogen. One report compared estrogen levels of both genders, showing an average 54-year-old man’s to be higher than an average 59-year-old woman’s.

Taking testosterone by itself, without monitoring other hormones, is not judicious. Testosterone may convert into even more estrogen, propagating its deleterious effects. However, through appropriate monitoring, therapy can be initiated to stop the conversion of testosterone to estrogen.

 

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